This project aims at Assessing the 5-year Effects of 500-day liquidified Petroleum Gas Cooking Intervention on health, Determining the exposure-response curves for HAP and health in four diverse LMIC populations and Determining relationships between LPG intervention and biomarkers of exposure/health effects. The Biomarker Centre will conduct both targeted and exploratory (metabolomics) analyses.
NIHR Clean- Air (Africa) Unit
“Clean modern energy for all” Benefiting health, Society, environment and Climate in Sub-saharan Africa to achieve the 2030 SDGs. This is a multi-site study with various aims including; Reducing ‘stacking’ with polluting fuels: Assessing the utility of pressure cookers to encourage exclusive use of clean fuel through time, fuel and cost savings. Addressing national priorities in Rwanda: Mapping of current fuel use practices for cooking, heating and lighting in public institutions. Facilitating clean cooking and enhanced nutrition in schools: Evaluation of impacts on air pollution and school fuel costs from a clean fuel and cooking innovations (pre-cooked beans and pressure cookers) intervention package in primary schools. Contrasting HAP exposure by fuel use: Quantifying levels of PM associated with polluting cooking fuels and LPG to model health impacts from clean cooking.
Post Caesarean Infections
The Post Caesarian Infections project is aimed to Determine the actual prevalence of post-Caesarean infection at hospitals in Rwanda; and identify hospital- and individual-level causal factors associated with these infections.
The Extended Spectrum beta-lactamas (ESBL) Carriage & Development of Surgical Site Infections in Rwanda is a project aimed to improve the Understanding of extended- spectrum beta-lactamase producing Enterobacateriaceae (ESBL-PE) carriage and its association with surgical site infections (SSI). We hypothesize that ESBL-PE carriage is a risk factor for ESBL-SSI and intervention targeted toward ESBL carriers can reduce the risk of SSI
The Combating Antimicrobial Resistance in Africa is a study a multi-site project implemented with various aims including; to develop an antibiogram based on phenotypic resistance profiles that can be easily referenced by clinicians to guide the choice of empiric antibiotics, to contribute to the global bacterial genome database, to evaluate the epidemiology, clinical risk factors and outcomes of human infections caused by MDR bacilli, to develop new screening tools that can guide judicious use of antibiotics, to improve our understanding of the dynamics of transmission of AMR genes, apply One Health principles to investigate the interactions between humans, animals and the environment, and utilize bacterial genomic data to develop new drugs that can be used for treatment in resource constrained settings, such as ours. This focus on children (0-5years) with serious Bacteria Infections.
Human Papilloma Virus
This study aims at comparing the Human Papillomavirus Nucleic Acid Amplification test kit (Assessment Reagent) with “Cobas HPV of Roche (Contrast Reagent), to verify the clinical performance of the assessment reagents and evaluate the applicability, effectiveness, and detection accuracy. Patients that will be found to HPV positive will be informed and guided/ referred for treatment.